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James R Beadle Selected Research

Ectromelia (Phocomelia)

5/2011Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine.
12/2009Antiviral evaluation of octadecyloxyethyl esters of (S)-3-hydroxy-2-(phosphonomethoxy)propyl nucleosides against herpesviruses and orthopoxviruses.
10/2006Synthesis and antiviral evaluation of alkoxyalkyl esters of acyclic purine and pyrimidine nucleoside phosphonates against HIV-1 in vitro.

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James R Beadle Research Topics

Disease

21Infections
06/2021 - 02/2002
10Cowpox
05/2011 - 08/2003
9Vaccinia
05/2011 - 01/2004
6Retinitis
01/2015 - 02/2002
4COVID-19
12/2021 - 01/2021
4Smallpox (Variola)
05/2011 - 08/2003
3Ectromelia (Phocomelia)
05/2011 - 10/2006
3Body Weight (Weight, Body)
01/2011 - 09/2004
2Cytomegalovirus Infections (Inclusion Disease)
01/2011 - 08/2004
2Neoplasms (Cancer)
01/2010 - 01/2006
2Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2010 - 01/2006
2Virus Diseases (Viral Diseases)
07/2009 - 06/2007
2HIV Infections (HIV Infection)
12/2008 - 08/2006
2Poxviridae Infections
11/2007 - 02/2004
2Infectious Ectromelia
03/2007 - 01/2004
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018
1Papillomavirus Infections
01/2018
1Leukemia
01/2018
1Retinal Diseases
01/2015
1Toxic Optic Neuropathy
01/2012
1Proliferative Vitreoretinopathy
01/2012
1Cytomegalovirus Retinitis
04/2011
1Melanoma (Melanoma, Malignant)
03/2011
1Uterine Cervical Dysplasia
01/2010
1Edema (Dropsy)
10/2007
1Inflammation (Inflammations)
10/2007
1Contagious Ecthyma
07/2007
1Retinoblastoma (Glioblastoma, Retinal)
01/2006
1Respiratory Tract Infections (Respiratory Tract Infection)
05/2004
1Acquired Immunodeficiency Syndrome (AIDS)
08/2003
1Cataract (Cataracts)
02/2002

Drug/Important Bio-Agent (IBA)

19EstersIBA
10/2018 - 01/2004
18Cidofovir (Vistide)FDA Link
01/2015 - 01/2004
14Antiviral Agents (Antivirals)IBA
06/2021 - 02/2002
10brincidofovirIBA
01/2015 - 02/2004
10LipidsIBA
01/2015 - 01/2004
9NucleosidesIBA
10/2018 - 10/2006
8ProdrugsIBA
01/2018 - 05/2004
7Organophosphonates (Phosphonates)IBA
01/2018 - 10/2006
6Pharmaceutical PreparationsIBA
06/2021 - 02/2002
69- (S)- (3- hydroxy- 2- (phosphonomethoxy)propyl)adenineIBA
08/2008 - 03/2006
5Ether (Diethyl Ether)IBA
09/2004 - 01/2004
4remdesivirIBA
12/2021 - 01/2021
4Retinaldehyde (Retinal)IBA
03/2011 - 02/2002
39-((2-phosphonylmethoxy)ethyl)guanineIBA
01/2018 - 01/2010
3AdenineFDA LinkGeneric
11/2007 - 07/2007
2molnupiravirIBA
06/2021 - 01/2021
2nirmatrelvirIBA
06/2021 - 01/2021
2Cytarabine (Cytosar-U)FDA LinkGeneric
01/2018 - 01/2012
2DNA (Deoxyribonucleic Acid)IBA
05/2011 - 01/2006
2GuanineIBA
01/2010 - 12/2009
2Tenofovir (Viread)FDA Link
10/2007 - 02/2007
2SaltsIBA
01/2006 - 02/2002
1Anti-Retroviral Agents (Antiretroviral Agents)IBA
11/2019
1adefovirIBA
01/2018
1MicellesIBA
01/2015
1hexadecyloxypropyl cytarabine 3',5'-cyclic monophosphateIBA
01/2012
1hexadecyloxypropyl cytarabine 5'-monophosphateIBA
01/2012
1octadecyloxyethyl-cyclic-cidofovirIBA
04/2011
1octadecyloxyethyl 9-(2-(phosphonomethoxy)ethyl)guanineIBA
01/2010
1ThymineIBA
12/2009
19- (3- hydroxy- 2- phosphonomethoxypropyl)- 2,6- diaminopurineIBA
12/2009
19- (3- hydroxy- 2- phosphonomethoxypropyl)guanineIBA
12/2009
1cyclic- 9- (3- hydroxy- 2- phosphonylmethoxypropyl)adenineIBA
10/2007
1hexadecyloxypropyl 9-(2-(phosphonomethoxy)propyl)adenineIBA
10/2007
1CytosineIBA
07/2007
1adefovir dipivoxil (Hepsera)FDA Link
02/2007
1Oncogene Proteins (Oncogene Protein)IBA
01/2006
1hexadecyloxypropyl-cyclic cidofovirIBA
06/2005
1purineIBA
05/2004
1Ribavirin (Virazole)FDA LinkGeneric
05/2004
1Smallpox Vaccine (Vaccine, Smallpox)FDA Link
01/2004
1Investigational DrugsIBA
01/2004
1VaccinesIBA
08/2003
11- O- hexadecyl- propanediol- 3- phospho- ganciclovirIBA
02/2002
1Ammonium CompoundsIBA
02/2002

Therapy/Procedure

8Therapeutics
01/2011 - 02/2002
2Intravenous Administration
12/2021 - 08/2021
2Intravitreal Injections
01/2015 - 02/2002
2Injections
10/2007 - 02/2002
1Oral Administration
08/2008